FACTS AROUND CAUSES ASSOCIATED WITH CONGENITAL DIAPHRAGMATIC HERNIA
Though the causes of diaphragmatic hernia in most cases are
unknown, researchers believe that some instances of diaphragmatic hernia may be
related to abnormalities in the baby’s genes.
• 10 to 15 percent of
the CDH cases are related to having syndromes such as Donnai-Barrow syndrome,
Fryns syndrome, and Pallister-Killian mosaic syndrome. These conditions are
again related to changes in genes.
• Around one fourth
of the CDH cases are associated to abnormalities of one or more major body
systems like heart, brain, skeleton, intestines, genitals, kidneys, or eyes.
These abnormalities could result from a common underlying condition though no
specific pointers could be made.
• 50 to 60 of the CDH
cases are isolated. That means it occurs with no other major malformations.
• Majority of the CDH
cases have no known genetic syndrome or chromosomal abnormality
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